Pseudoexfoliation syndrome and pseudoexfoliative glaucoma

Background

Pseudoexfoliative glaucoma (PXG) is a common secondary glaucoma that occurs when pigment and abnormal basement membrane material from anterior segment anatomical structures deposit in the trabecular meshwork. This anomaly arises from the predisposing condition, pseudoexfoliation syndrome (PXE). Complications are common, making this one of the most difficult glaucomas to manage.

Purpose

The literature is reviewed in order to facilitate understanding of this condition.

Key Words: Basement membrane, fibrillopathy, pigment, pseudoexfoliation, secondary glaucoma

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